KIF7 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Western blot analysis of extracts of various cell lines using KIF7 Polyclonal Antibody at 1:1000 dilution.
Product Name
KIF7 Polyclonal Antibody
Catalog Number
RD88257A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Immunogen Information
Immunogen
Recombinant fusion protein of human KIF7
Gene ID
374654
Swissprot
Q2M1P5
Synonyms
KIF7ACLSAGBKHLS2JBTS12UNQ340
Calculated MW
23kDa/28kDa
Observed MW
38KDa
Applications
Research Areas