Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Immunogen Information
Immunogen
Recombinant Human KLK10 protein expressed by E.coli
Swissprot
O43240
Synonyms
Breast normal epithelial cell associated serine proteaseKallikrein related peptidase 10Kallikrein10KLK 10KLK10NES 1NES1Normal epithelial cell-specific 1Protease serine like 1Protease serine-like 1PRSS L1PRSSL 1PRSSL1
Calculated MW
12kDa
Observed MW
11kDa
Applications
Reactivity
Human
Tested Applications
WB,IHC
Conjugation
Unconjugated
Dilution
WB 1:500-1:1000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.