Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Recombinant protein of human KLK8
Swissprot
O60259
Synonyms
Brain serine protease 1BSP1hK8HNPHPNKallikrein 8 (neuropsin/ovasin)Kallikrein related peptidase 8Kallikrein-8Kallikrein8KLK 8Klk8KLK8 protein type 1KLK8 protein type 2KLK8Neuropsinneuropsin type 1Neuropsin type 1includedNeuropsin type 2
Gene Accession
NP_009127
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:100-1:300
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4