KLRC1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD80871A
Western blot analysis of extracts of various cell lines using KLRC1 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using KLRC1 Polyclonal Antibody at dilution of 1:1000.
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Overview

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Product Name
KLRC1 Polyclonal Antibody
Catalog Number
RD80871A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Immunogen Information

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Immunogen
Recombinant fusion protein of human KLRC1 (NP_015567.1).
Gene ID
3821
Swissprot
P26715
Synonyms
KLRC1CD159ANKG2NKG2A
Calculated MW
24 kDa/26 kDa
Observed MW
26 kDa

Applications

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Reactivity
Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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