KNG1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD266907A
Western blot analysis of extracts of HT-29 cells using KNG1 Polyclonal Antibody at dilution of 1:1000.
Product Name
KNG1 Polyclonal Antibody
Catalog Number
RD266907A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant fusion protein of human KNG1 (NP_000884.1).
Gene ID
3827
Swissprot
P01042
Synonyms
KNG1BDKBKKNG
Calculated MW
43 kDa/47 kDa/71 kDa
Observed MW
68 kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas