KRR1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD252736A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using KRR1 Polyclonal Antibody at dilution of 1:50(×200)
Product Name
KRR1 Polyclonal Antibody
Catalog Number
RD252736A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU). KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.
Immunogen Information
Immunogen
Fusion protein of human KRR1
Swissprot
Q13601
Synonyms
HIV 1 Rev binding protein 2HIV-1 Rev-binding protein 2HRB2KRR1KRR1 small subunit processome component homologKRR1small subunit (SSU) processome componenthomolog (yeast)KRR1Rev interacting protein 1Rev-interacting protein 1RIP 1Rip-1
Gene Accession
BC016778
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.