This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
Immunogen Information
Immunogen
Full length fusion protein
Swissprot
Q14847
Synonyms
LASP 1LASP-1LASP1LASP1LIM and SH3 domain protein 1LIM and SH3 protein 1Metastatic lymph node gene 50 proteinMLN 50MLN50OTTHUMP00000164238OTTHUMP00000164239