LAT Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89688A
Western blot analysis of extracts of THP-1 cells using LAT Polyclonal Antibodyat 1:1000 dilution.
Product Name
LAT Polyclonal Antibody
Catalog Number
RD89688A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Recombinant fusion protein of human LAT
Gene ID
27040
Swissprot
O43561
Synonyms
LATLAT1pp36IMD52
Calculated MW
85kDa/91kDa/92kDa/94kDa/96kDa/98kDa
Observed MW
95KDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas