LATS2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78673A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using LATS2 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using LATS2 Polyclonal Antibody at dilution 1:30
Variation
Quantity
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Overview
Product Name
LATS2 Polyclonal Antibody
Catalog Number
RD78673A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
Immunogen Information
Immunogen
Synthetic peptide of human LATS2
Swissprot
Q9NRM7
Synonyms
FLJ13161Kinase phosphorylated during mitosis proteinKPMLarge tumor suppressor homolog 2Large tumor suppressor homolog 2 DrosophilaLarge tumor suppressor kinase 2LATS large tumor suppressor Drosophila homolog 2LATS large tumor suppressor homolog 2L
Gene Accession
NP_055387
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.5 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas