For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80562A
Western blot analysis of extracts of various cell lines using LC3B Polyclonal Antibody at dilution of 1:1000.
Immunohistochemistry of paraffin-embedded Rat brain using LC3B Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse brain using LC3B Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of LC3B knockout 293T cells treated by chloroquine (top left) and wild-type 293T cells (top middle),wild-type 293T cells treated by chloroquine (top right) using LC3B Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.