Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. Plays a role in the development of interneurons and motor neurons in cooperation with LHX3 and ISL1. Acts synergistically with LHX1/LIM1 in axis formation and activation of gene expression. Acts with LMO2 in the regulation of red blood cell development, maintaining erythroid precursors in an immature state (By similarity).
Immunogen Information
Immunogen
Fusion protein of human LDB1
Swissprot
Q86U70
Synonyms
Carboxyl Terminal LIM Domain Binding 2Carboxyl-terminal LIM domain-binding protein 2CLIM 2CLIM-2hLdb1LDB-1ldb1LDB1LIM Domain Binding 1LIM domain binding factor CLIM2LIM domain-binding factor CLIM2LIM domain-binding protein 1NLINuclear LIM Do