Lgals3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD86694A
Western blot with Lgals3 Polyclonal antibody at dilution of 1:500.lane 1: Hela whole cell lysate, lane 2:MCF-7 whole cell lysate, lane 3:A431 whole cell lysate,lane 4：RAW264.7 whole cell lysate,lane 5:NIH/3T3 whole cell lysate,lane 6: C6 whole cell lysate
Variation
Quantity
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Overview
Product Name
Lgals3 Polyclonal Antibody
Catalog Number
RD86694A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
Immunogen Information
Immunogen
Recombinant Rat Lgals3 protein expressed by E.coli
Swissprot
P08699
Synonyms
LGALS3MAC2Galectin-3Gal-335 kDa lectinCBP 35Galactose-specific lectin 3GALBPIgE-binding proteinL-31Laminin-binding proteinLectin L-29Mac-2 antigen
Calculated MW
29kDa
Observed MW
30kDa
Applications
Reactivity
Human,mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:250-1:500
Concentration
1.7mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas