LIN28B Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76665A
Western Blot analysis of Mouse liver tissue and k562 cell, hela and 293T cell using LIN28B Polyclonal Antibody at dilution of 1:550
Product Name
LIN28B Polyclonal Antibody
Catalog Number
RD76665A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
Immunogen Information
Immunogen
Synthetic peptide of human LIN28B
Swissprot
Q6ZN17
Synonyms
CSDD 2CSDD2FLJ16517Lin 28 homolog B (C. elegans)Lin 28.2Lin-28BLIN28BLN28BProtein lin-28 homolog B
Calculated MW
27 kDa
Gene Accession
NP_001004317
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas