Lipin 1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD89902A
Western blot analysis of extracts of rat skeletal muscle using Lipin 1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of rat skeletal muscle using Lipin 1 Polyclonal Antibody at 1:1000 dilution.
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Overview

Circle
Product Name
Lipin 1 Polyclonal Antibody
Catalog Number
RD89902A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

Circle
This gene encodes a magnesium-ion-dependent phosphatidic acid phosphohydrolase enzyme that catalyzes the penultimate step in triglyceride synthesis including the dephosphorylation of phosphatidic acid to yield diacylglycerol. Expression of this gene is required for adipocyte differentiation and it also functions as a nuclear transcriptional coactivator with some peroxisome proliferator-activated receptors to modulate expression of other genes involved in lipid metabolism. Mutations in this gene are associated with metabolic syndrome, type 2 diabetes, and autosomal recessive acute recurrent myoglobinuria (ARARM). This gene is also a candidate for several human lipodystrophy syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their full-length structures have not been determined.

Immunogen Information

Circle
Immunogen
Recombinant fusion protein of human Lipin 1
Gene ID
23175
Swissprot
Q14693
Synonyms
LPIN1PAP1lipin 1
Calculated MW
43kDa/138kDa
Observed MW
145kDa

Applications

Circle
Reactivity
Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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