LMNA Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD71399A
Western Blot analysis of 3T3 cells using LMNA Polyclonal Antibody at dilution of 1:2000.
Immunohistochemistry of paraffin-embedded Human uterus tissue using LMNA Polyclonal Antibody at dilution of 1:200.
Immunofluorescence analysis of Human liver tissue using LMNA Polyclonal Antibody at dilution of 1:200.
Product Name
LMNA Polyclonal Antibody
Catalog Number
RD71399A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Synthesized peptide derived from human Lamin A/C around the non-phosphorylation site of Ser392.
Swissprot
P02545
Synonyms
70 kDa laminCardiomyopathy dilated 1A (autosomal dominant)CDCD1CDDCCMD1ACMT2B1EMD2FPLFPLDFPLD2HGPSIDCLamin ALamin A/CLamin A/C like 1LaminLamin CLamin-A/CLDP1LFPLGMD1BLimb girdle muscular dystrophy 1B (autosomal dominant)LMN 1LMN A
Calculated MW
74 kDa
Observed MW
74 kDa,65 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas