Leucine-rich repeats and immunoglobulin-like domains protein 1is aproteinthat in humans is encoded by theLRIG1gene.It encodes atransmembrane proteinthat has been shown to interact with receptor tyrosine kinases of theEGFR-family,METandRET. Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
Immunogen Information
Immunogen
Synthetic peptide of human LRIG1
Swissprot
Q96JA1
Synonyms
Leucine rich repeat proteinLeucine rich repeat protein LRIG1leucine rich repeats and immunoglobulin like domains 1Leucine-rich repeats and immunoglobulin-like domains protein 1leucine-rich repeats- and immunoglobulin-like domains-cotnaining protein 1
Gene Accession
NP_056356
Applications
Reactivity
Human
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4