LRPAP1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD76343A
Western Blot analysis of 293T cell and fetal kidney tissue using LRPAP1 Polyclonal Antibody at dilution of 1:1600
Immunohistochemistry of paraffin-embedded Human colon cancer using LRPAP1 Polyclonal Antibody at dilution of 1:100
Product Name
LRPAP1 Polyclonal Antibody
Catalog Number
RD76343A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Low density lipoprotein receptor-related protein associated protein 1also known asLRPAP1orRAPis a chaperoneproteinwhich in humans is encoded by the LRPAP1gene. LRPAP1 is involved with trafficking of certain members of the LDL receptor family including LRP1 and LRP2. It is a glycoprotein that binds to the alpha-2-macroglobulin receptor, as well as to other members of the low density lipoprotein receptor family. It acts to inhibit the binding of all know ligands for these receptors, and may prevent receptor aggregation and degradation in the endoplasmic reticulum, thereby acting as a molecular chaperone. It may be under the regulatory control of calmodulin, since it is able to bind calmodulin and be phosphorylated by calmodulin-dependent kinase II.
Immunogen Information
Immunogen
Synthetic peptide of human LRPAP1
Swissprot
P30533
Synonyms
39 kDa receptor-associated proteinA2MRAPA2RAPAlpha 2 macroglobulin receptor associated proteinAlpha 2 MRAPAlpha-2-macroglobulin receptor-associated proteinAlpha-2-MRAPAMRPHBP44Lipoprotein receptor associated proteinLow density lipoprotein recept
Calculated MW
41 kDa
Gene Accession
NP_002328
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas