LRRC16A Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD217767A
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using LRRC16A Polyclonal Antibody at dilution of 1:40(×200)
Product Name
LRRC16A Polyclonal Antibody
Catalog Number
RD217767A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).
Immunogen Information
Immunogen
Synthetic peptide of human LRRC16A
Swissprot
Q5VZK9
Synonyms
Acan 125Capping proteinArp2/3and myosin I linkerCARMIL homologleucine rich repeat containing 16Leucine-rich repeat-containing protein 16ALR16ALrrc16 proteinLRRC16Ap116
Gene Accession
NP060110
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:30-1:150, ELISA 1:5000-1:10000
Concentration
0.6 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas