Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3' and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Immunogen Information
Immunogen
Recombinant fusion protein of human LRRFIP1
Gene ID
9208
Swissprot
Q32MZ4
Synonyms
LRRFIP1FLAP-1FLAP1FLIIAP1GCF-2GCF2HUFI-1TRIP
Calculated MW
52kDa/57kDa
Observed MW
60kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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