Lrwd1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89391A
Western blot analysis of extracts of various cell lines using Lrwd1 Polyclonal Antibody at 1:1000 dilution.
Variation
Quantity
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Overview
Product Name
Lrwd1 Polyclonal Antibody
Catalog Number
RD89391A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
A synthetic peptide of human Lrwd1
Gene ID
222229
Swissprot
Q9UFC0
Synonyms
LRWD1CENP-33ORCAleucine-rich repeat and WD repeat-containing protein 1
Calculated MW
50kDa/54kDa
Observed MW
49KDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.