Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP of histone pre-mRNA in a U7 snRNP dependent manner.
Immunogen Information
Immunogen
Recombinant fusion protein of human LSM10
Gene ID
84967
Swissprot
Q969L4
Synonyms
LSM10MST074MSTP074
Calculated MW
49kDa/73kDa/155kDa
Observed MW
150-155kDa
Applications
Reactivity
Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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