This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic Peptide
Swissprot
P02788
Synonyms
GIG12Growth inhibiting protein 12HLF2Kaliocin 1LactoferrinLactoferroxin-CLactotransferrinLFLTFNeutrophil lactoferrinTalalactoferrinTRFL
Applications
Reactivity
Human
Tested Applications
IHC-p,IF,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-300, IF 1:50-1:200, ELISA 1:5000-10000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.