The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Fusion protein of human LYRM1
Swissprot
O43325
Synonyms
1110065L10Rik2310004B22Rik4930404J24RikA211C6.1LYR motif containing 1LYR motif containing protein 1LYR motif-containing protein 1LYRM 1lyrm1LYRM1OTTHUMP00000162292OTTMUSP00000031126OTTMUSP00000031127OTTMUSP00000031128OTTMUSP00000031129RGD15
Gene Accession
BC017039
Applications
Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
0.72 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
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