LZTS1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD88596A
Western blot analysis of extracts of Rat brain using LZTS1 Polyclonal Antibody at 1:3000 dilution.
Western blot analysis of extracts of various cell lines using LZTS1 Polyclonal Antibody at 1:3000 dilution.
Product Name
LZTS1 Polyclonal Antibody
Catalog Number
RD88596A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Immunogen Information
Immunogen
Recombinant fusion protein of human LZTS1
Gene ID
11178
Swissprot
Q9Y250
Synonyms
LZTS1F37FEZ1
Calculated MW
122kDa/135kDa
Observed MW
130kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas