The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Immunogen Information
Immunogen
Recombinant protein of human MAD2L1BP
Swissprot
Q15013
Synonyms
Caught by MAD2 proteinCMT2dJ261G23.1KIAA0110MAD2L1 binding proteinMAD2L1 binding protein isoform 2MAD2L1-binding proteinMad2l1bpMD2BPMGC11282OTTHUMP00000016496RP1 261G23.6
Calculated MW
31 kDa
Gene Accession
BC002904
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:50-1:200
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4