MAP1LC3B Monoclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD85553A
Immunohistochemistry of paraffin-embedded Human brain tissue using MAP1LC3B Monoclonal Antibody at dilution of 1:200.
Immunohistochemistry of paraffin-embedded Human brain tissue using MAP1LC3B Monoclonal Antibody at dilution of 1:200.
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Overview

Circle
Product Name
MAP1LC3B Monoclonal Antibody
Catalog Number
RD85553A
Clonality
Monoclonal
Purification Method
Protein A purification
Isotype
IgG
Host
Mouse

Background

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The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component. MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2.

Immunogen Information

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Immunogen
Recombinant Protein of LC3B of MAP1LC3B
Swissprot
Q9GZQ8
Synonyms
ATG8FAutophagy-related protein LC3 BAutophagy-related ubiquitin-like modifier LC3 BLC3BLC3IIMAP1 light chain 3 like protein 2MAP1 light chain 3-like protein 2MAP1A/1BLC3MAP1A/MAP1B LC3 BMAP1A/MAP1B light chain 3 BMAP1ALC3MAP1LC3B aMap1lc3bMic

Applications

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Reactivity
Human
Tested Applications
IHC-p
Conjugation
Unconjugated
Dilution
IHC 1:100-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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