The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 Beta) is a Protein Coding gene. Diseases associated with MAP1LC3B include Sporadic Pheochromocytoma and Lacrimal Gland Adenocarcinoma. Among its related pathways are Vesicle-mediated transport and Senescence and Autophagy in Cancer. GO annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B2.
Immunogen Information
Immunogen
Recombinant Protein of LC3B of MAP1LC3B
Swissprot
Q9GZQ8
Synonyms
ATG8FAutophagy-related protein LC3 BAutophagy-related ubiquitin-like modifier LC3 BLC3BLC3IIMAP1 light chain 3 like protein 2MAP1 light chain 3-like protein 2MAP1A/1BLC3MAP1A/MAP1B LC3 BMAP1A/MAP1B light chain 3 BMAP1ALC3MAP1LC3B aMap1lc3bMic
Applications
Reactivity
Human
Tested Applications
IHC-p
Conjugation
Unconjugated
Dilution
IHC 1:100-200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4