The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. It contains 3 Tau/MAP repeats. Phosphorylated at serine residues in K-X-G-S motifs by causing MAP/microtubule affinity-regulating kinase (MARK1 or MARK2), detachment from microtubules, and their disassembly.
Immunogen Information
Immunogen
KLH conjugated Synthetic peptide corresponding to Mouse MAP2
Swissprot
P20357,P15146
Synonyms
DKFZp686I2148MAP 2MAP dendrite specificMAP-2MAP2MAP2AMAP2BMAP2CMicrotubule associated protein 2Microtubule-associated protein 2MTAP2.
Calculated MW
70/280 kDa
Observed MW
280 kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
3.5 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4