MAP2K5 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75302A
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MAP2K5 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using MAP2K5 Polyclonal Antibody at dilution 1:40
Product Name
MAP2K5 Polyclonal Antibody
Catalog Number
RD75302A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
Immunogen Information
Immunogen
Recombinant protein of human MAP2K5
Swissprot
Q13163
Synonyms
Dual specificity mitogen activated protein kinase kinase 5Dual specificity mitogen-activated protein kinase kinase 5EC 2.7.12.2HsT17454MAP kinase kinase 5MAP kinase kinase MEK5bMAP2K5MAPK/ERK kinase 5MAPKK 5MAPKK5MEK 5mitogen-activated protein
Gene Accession
BC008838
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.4 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas