MAP3K12 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MAP3K12 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MAP3K12 Polyclonal Antibody at dilution 1:30
Product Name
MAP3K12 Polyclonal Antibody
Catalog Number
RD75373A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.
Immunogen Information
Immunogen
Recombinant protein of human MAP3K12
Swissprot
Q12852
Synonyms
DlkDual leucine zipper bearing kinaseDual leucine zipper kinase DLKLeucine-zipper protein kinaseM3K12Map3k12MAPK-upstream kinaseMEKK12Mitogen-activated protein kinase kinase kinase 12Mixed lineage kinaseMUKProtein kinase MUKZPKZPKP1
Gene Accession
BC050050
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:25-1:100
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas