MAP4K4 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87358A
Western blot analysis of extracts of various cell lines using MAP4K4 Polyclonal Antibody at 1:3000 dilution.
Product Name
MAP4K4 Polyclonal Antibody
Catalog Number
RD87358A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen Information
Immunogen
Recombinant fusion protein of human MAP4K4
Gene ID
9448
Swissprot
O95819
Synonyms
MAP4K4FLH21957HEL-S-31HGKMEKKK4NIK
Calculated MW
298kDa/304kDa
Observed MW
290kDa
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas