MAPKAPK3 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD253182A
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue  using MAPKAPK3 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human gastric cancer tissue using MAPKAPK3 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue  using MAPKAPK3 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using MAPKAPK3 Polyclonal Antibody at dilution of 1:60(×200)
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Overview

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Product Name
MAPKAPK3 Polyclonal Antibody
Catalog Number
RD253182A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein.

Immunogen Information

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Immunogen
Fusion protein of human MAPKAPK3
Swissprot
Q16644
Synonyms
3pKanti MAPKAPK3Chromosome 3p kinaseEC 2.7.11.1MAP kinase-activated protein kinase 3MAPK activated protein kinase 3MAPK-activated protein kinase 3MAPK3MAPKAPMAPKAP kinase 3MAPKAP-K3MAPKAP3MAPKAPK 3MAPKAPK-3Mapkapk3MAPKAPK3Mitogen activated
Gene Accession
BC001662

Applications

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Reactivity
Human, Mouse, Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200, ELISA 1:5000-1:10000
Concentration
0.9 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

Research Areas

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