MAPKBP1 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD87479A
Western blot analysis of extracts of various cell lines using MAPKBP1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using MAPKBP1 Polyclonal Antibody at 1:1000 dilution.
Variation
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Overview
Circle
Product Name
MAPKBP1 Polyclonal Antibody
Catalog Number
RD87479A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Circle
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients.
Immunogen Information
Circle
Immunogen
A synthetic peptide of human MAPKBP1
Gene ID
23005
Swissprot
O60336
Synonyms
MAPKBP1JNKBP-1JNKBP1NPHP20
Calculated MW
14kDa/17kDa/26kDa
Observed MW
26kDa
Applications
Circle
Reactivity
Human,Mouse
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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