MARK1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD85097A
Immunohistochemistry of paraffin-embedded Mouse lung using MARK1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Product Name
MARK1 Polyclonal Antibody
Catalog Number
RD85097A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
MAP/microtubule affinity-regulating kinase 1 (MARK1) is a 795 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. MARK1 is thought to play a role in the stability of the microtubule matrix of the cytoskeleton. MARK1 is activated by phosphorylation of Thr215 by LKB1 in complex with STRAD and MO25. Localized to the cytoskeleton, MARK1 contains one kinase-associated (KA1) domain, one protein kinase domain and one UBA domain. Expressed as three isoforms produced by alternative splicing, MARK1 is found with highest levels in brain, skeletal muscle and heart.
Immunogen Information
Immunogen
Recombinant fusion protein of human MARK1 (NP_061120.3).
Gene ID
4139
Swissprot
Q9P0L2
Synonyms
MARK1MARKPar-1cPar1c
Applications
Reactivity
Human,Mouse
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas