This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human MARK2
Swissprot
Q7KZI7
Synonyms
ELKL motif kinase 1ELKL motif kinaseEMK-1EMK1MAP/microtubule affinity regulating kinase 2MAP/microtubule affinity-regulating kinase 2Mark2MARK2MGC99619PAR 1Par 1bPAR1 homologPar1bSer/Thr protein kinase PAR 1BSerine/threonine protein kinase E