MBP Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD70466A
Immunohistochemistry analysis of paraffin-embedded mouse brain  using MBP Polyclonal Antibody at dilution of 1:600.
Immunohistochemistry analysis of paraffin-embedded mouse brain using MBP Polyclonal Antibody at dilution of 1:600.
Immunohistochemistry analysis of paraffin-embedded rat brain  using MBP Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat brain using MBP Polyclonal Antibody at dilution of 1:300.
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Overview

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Product Name
MBP Polyclonal Antibody
Catalog Number
RD70466A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.

Immunogen Information

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Immunogen
Recombinant protein corresponding to Mouse Myelin Basic Protein
Swissprot
P04370,P02688
Synonyms
GDBGolli MBPGolli MBPmyelin basic proteinHemopoietic MBPHMBPRHUGOMBPMBP_CAVPOMBPMGC99675MLDMyelin A1 proteinMyelin A1 ProteinbasicMyelin basic proteinMyelin DeficientMyelin membrane encephalitogenic proteinOTTHUMP00000163776OTTHUMP00000

Applications

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Reactivity
Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:300-1:1000
Concentration
100 μg/mL
Storage Buffer
PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.

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