MCAM Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD81646A
Immunohistochemistry of paraffin-embedded Human colon using MCAM Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human colon carcinoma using MCAM Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast using MCAM Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human breast cancer using MCAM Polyclonal Antibody at dilution of 1:100 (40x lens).
Product Name
MCAM Polyclonal Antibody
Catalog Number
RD81646A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
CD146,also known as melanoma cell adhesion molecule (MCAM) or MUC18,originally identified as a biomarker of melanoma progression,is a transmembrane glycoprotein belonging to the immunoglobulin (Ig) superfamily . Structurally,it consists of five Ig domains,a transmembrane domain,and a cytoplasmic region. In normal adult tissue,CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis,and has been used as marker of circulating endothelium cells (CECs) .
Immunogen Information
Immunogen
Recombinant fusion protein of human MCAM (NP_006491.2).
Gene ID
4162
Swissprot
P43121
Synonyms
MCAMCD146MUC18
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas