This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Immunogen Information
Immunogen
Synthetic peptide of human MCL1
Swissprot
Q07820
Synonyms
Bcl 2 related protein EAT/mcl1Bcl-2-like protein 3Bcl-2-related protein EAT/mcl1BCL2 relatedBcl2-L-3BCL2L3EATInduced myeloid leukemia cell differentiation protein Mcl 1Induced myeloid leukemia cell differentiation protein Mcl-1MCL 1MCL1MCL1-ES
Gene Accession
NP_068779
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.7 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4