MCM2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77502A
Immunohistochemistry of paraffin-embedded Human lung cancer tissue using MCM2 Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MCM2 Polyclonal Antibody at dilution 1:50
Product Name
MCM2 Polyclonal Antibody
Catalog Number
RD77502A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex witHuman, MouseCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Immunogen Information
Immunogen
Recombinant protein of human MCM2
Swissprot
P49736
Synonyms
BM28CCNL 1CCNL1CDC like 1cdc19CDCL 1CDCL1Cell devision cycle like 1Cyclin like 1D3S3194DNA replication licensing factor MCM2KIAA0030MCM 2MCM2MCM2 minichromosome maintenance deficient 2 mitotinMCM2 minichromosome maintenance deficient 2 mito
Gene Accession
BC007670
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas