MCM3 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD75264A
Western Blot analysis of K562, Jurkat, hela and 293T cell using MCM3 Polyclonal Antibody at dilution of 1:550
Product Name
MCM3 Polyclonal Antibody
Catalog Number
RD75264A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly witHuman, MouseCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
Recombinant protein of human MCM3
Swissprot
P25205
Synonyms
Cervical cancer proto oncogene 5DNA polymerase alpha holoenzyme associated P1DNA polymerase alpha holoenzyme associated protein P1DNA polymerase alpha holoenzyme-associated protein P1DNA replication factor MCM3DNA replication licensing factor mcm3HC
Calculated MW
91 kDa
Gene Accession
BC001626
Applications
Reactivity
Human,Mouse
Tested Applications
WB,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas