MCM6 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77501A
Western Blot analysis of 293T, A549, Raji, K562 and NIH/3T3 cell using MCM6 Polyclonal Antibody at dilution of 1:433.3
Immunohistochemistry of paraffin-embedded Human esophagus cancer using MCM6 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human colon cancer using MCM6 Polyclonal Antibody at dilution of 1:60
Product Name
MCM6 Polyclonal Antibody
Catalog Number
RD77501A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Immunogen Information
Immunogen
Recombinant protein of human MCM6
Swissprot
Q14566
Synonyms
DNA replication licensing factor MCM6MCG40308Mcm6MCM6 minichromosome maintenance deficient 6 (MIS5 homologS. pombe)MCM6 minichromosome maintenance deficient 6MCM6Minichromosome maintenance complex component 6Minichromosome maintenance deficient (m
Calculated MW
93 kDa
Gene Accession
BC032374
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000, IHC 1:100-1:300
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas