MCTS1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD78235A
Western Blot analysis of Jurkat and PC3 cell using MCTS1 Polyclonal Antibody at dilution of 1:200
Immunohistochemistry of paraffin-embedded Human thyroid cancer using MCTS1 Polyclonal Antibody at dilution of 1:60
Immunohistochemistry of paraffin-embedded Human brain using MCTS1 Polyclonal Antibody at dilution of 1:60
Product Name
MCTS1 Polyclonal Antibody
Catalog Number
RD78235A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
MCTS1 (malignant T cell amplified sequence 1), also known as MCT1, is a 181 amino acid protein that is ubiquitously expressed and localizes to the cytoplasm of cells. MCTS1 may play a role in cell cycle regulation by decreasing cell doubling time and by shortening the duration of G1 transit time and G1/S transition. The protein level of Cdk4 and Cdk6 kinases activity and cyclin D1 is enhanced by expression of MCTS1. As a translation enhancer, MCTS1 recruits DENR and binds to the cap complex of the 5'-terminus of mRNAs, subsequently altering the mRNA translation profile. MCTS1 promotes lymphoid tumor development and contributes to the pathogenesis and progression of breast cancer. MCTS1 positively regulates phosphorylation of ERK1 and ERK2.
Immunogen Information
Immunogen
Recombinant protein of human MCTS1
Swissprot
Q9ULC4
Synonyms
FLJ39637Malignant T cell-amplified sequence 1MCT 1MCT-1MCT1MCTS 1MCTS1MCTS1Multiple copies T cell malignancies 1Multiple copies T cell malignanciesMultiple copies T-cell malignanciesOncogene MCT 1Oncogene MCT1
Calculated MW
21 kDa
Gene Accession
BC001013
Applications
Reactivity
Human
Tested Applications
WB,IHC,ELISA
Conjugation
Unconjugated
Dilution
WB 1:200-1:1000, IHC 1:100-1:300
Concentration
0.2 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas