MECOM Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD219826A
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MECOM Polyclonal Antibody at dilution of 1:60(×200)
Product Name
MECOM Polyclonal Antibody
Catalog Number
RD219826A
Clonality
Polyclonal
Purification Method
Antigen affinity purification
Isotype
IgG
Host
Rabbit
Background
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
Immunogen Information
Immunogen
Synthetic peptide of human MECOM
Swissprot
Q03112
Synonyms
Ecotropic Virus Integration Site 1 Protein HomologMDS1 And EVI1 Complex Locus ProteinPR Domain 3EVI1MDS1MDS1 And EVI1 Complex Locus Protein EVI1MDS1 And EVI1 Complex Locus Protein MDS1Ecotropic Viral Integration Site 1Myelodysplasia Syndrome 1 Pro
Gene Accession
NP005232
Applications
Reactivity
Human, Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:40-1:200, ELISA 1:5000-1:10000
Concentration
1.68 mg/mL
Storage Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas