The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Mediator. This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by this gene, mediator complex subunit 12 (MED12), along witHuman, MouseED13, CDK8 kinase, and cyclin C.
Immunogen Information
Immunogen
Synthetic peptide of human MED12
Swissprot
Q93074
Synonyms
Activator recruited cofactor 240 kDa componentActivator-recruited cofactor 240 kDa componentARC240CAG repeat protein 45CAGH45HOPAKIAA0192MED12MED12Mediator complex subunit 12Mediator of RNA polymerase II transcription subunit 12OPA containing p
Gene Accession
NP_005111
Applications
Reactivity
Human,Mouse
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.1 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4