MESDC2 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD87764A
Western blot analysis of extracts of various cell lines using MESDC2 Polyclonal Antibody at 1:3000 dilution.
Product Name
MESDC2 Polyclonal Antibody
Catalog Number
RD87764A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs. Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ formation by promoting cell-surface expression of LRP4 (By similarity. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE cells (By similarity.
Immunogen Information
Immunogen
Recombinant fusion protein of human MESDC2
Gene ID
23184
Swissprot
Q14696
Synonyms
MESDC2BOCAMESD
Calculated MW
48kDa
Observed MW
49kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas