Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val. Required for normal progression through the cell cycle.
Immunogen Information
Immunogen
Recombinant fusion protein of human METAP1
Gene ID
23173
Swissprot
P53582
Synonyms
METAP1MAP1AMetAP1A
Calculated MW
282kDa/299kDa/302kDa
Observed MW
302kDa
Applications
Reactivity
Mouse,Rat
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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