MFGE8 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD80870A
Western blot analysis of extracts of various cell lines using MFGE8 Polyclonal Antibody at dilution of 1:3000.
Immunofluorescence analysis of C6 cells using MFGE8 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of L929 cells using MFGE8 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using MFGE8 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
MFGE8 Polyclonal Antibody
Catalog Number
RD80870A
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
Immunogen Information
Immunogen
Recombinant fusion protein of human MFGE8 (NP_001108086.1).
Gene ID
4240
Swissprot
Q08431
Synonyms
MFGE8BA46EDIL1HMFGHsT19888MFG-E8MFGMOAcGD3SSED1SPAG10hP47
Calculated MW
35 kDa/37 kDa/43 kDa
Observed MW
54 kDa
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
WB,IF
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000 IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas