Major intrinsic protein is a member of the water-transporting aquaporins as well as the original member of the MIP family of channel proteins. The function of the fiber cell membrane protein encoded by this gene is undetermined, yet this protein is speculated to play a role in intracellular communication. The MIP protein is expressed in the ocular lens and is required for correct lens function. This gene has been mapped among aquaporins AQP2, AQP5, and AQP6, in a potential gene cluster at 12q13.
Immunogen Information
Immunogen
Synthetic peptide of human MIP
Swissprot
P30301
Synonyms
AQP 0AQP0AquaporinAquaporin-0Aquaporin0Lens fiber major intrinsic proteinLIM 1LIM1Major intrinsic protein 26kDMajor intrinsic protein of lens fiberMIP 26mipMIPMIP26MP 26MP26PALM
Gene Accession
NP_036196
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-200, ELISA 1:500-5000
Concentration
0.3 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4