MLH1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD77516A
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using MLH1 Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using MLH1 Polyclonal Antibody at dilution 1:60
Product Name
MLH1 Polyclonal Antibody
Catalog Number
RD77516A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Immunogen Information
Immunogen
Recombinant protein of human MLH1
Swissprot
P40692
Synonyms
COCA 2COCA2DNA mismatch repair protein Mlh1FCC 2FCC2hMLH 1hMLH1HNPCC 2HNPCCHNPCC2MGC5172MLH 1MLH1MLH1MutL homolog 1 (E. coli)MutL homolog 1MutL homolog 1 colon cancer nonpolyposis type 2MutL homolog 1colon cancernonpolyposis type 2 (E.
Gene Accession
BC006850
Applications
Reactivity
Human,Mouse,Rat
Tested Applications
IHC,ELISA
Conjugation
Unconjugated
Dilution
IHC 1:50-1:200
Concentration
0.8 mg/mL
Storage Buffer
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas