MLH1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
RD89410A
Western blot analysis of extracts of various cell lines using MLH1 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of Mouse thymus cells using MLH1 Polyclonal Antibody at 1:1000 dilution.
Variation
Quantity
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Overview
Product Name
MLH1 Polyclonal Antibody
Catalog Number
RD89410A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Immunogen Information
Immunogen
A synthetic peptide of human MLH1
Gene ID
4292
Swissprot
P40692
Synonyms
MLH1COCA2FCC2HNPCCHNPCC2hMLH1mutL homolog 1
Calculated MW
46kDa/60kDa/61kDa/63kDa/64kDa/66kDa
Observed MW
Refer to figures
Applications
Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1mg/mL
Storage Buffer
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Research Areas