MLH3 Polyclonal Antibody

For reference only. Please follow the manual included in your kit for instructions.

Catalog Number
RD86875A
Western blot analysis of extracts of various cell lines using MLH3 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using MLH3 Polyclonal Antibody at 1:1000 dilution.
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Overview

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Product Name
MLH3 Polyclonal Antibody
Catalog Number
RD86875A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Rabbit

Background

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This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Immunogen Information

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Immunogen
Recombinant fusion protein of human MLH3
Gene ID
27030
Swissprot
Q9UHC1
Synonyms
MLH3HNPCC7
Calculated MW
30kDa
Observed MW
30kDa

Applications

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Reactivity
Human
Tested Applications
WB
Conjugation
Unconjugated
Dilution
WB 1:500-1:2000
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Instructions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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